2008

2008 hat das CRTD zehn Forschungsprojekte innerhalb des CRTD Netzwerkes bewilligt. 

Dr. Marius Ader  / Dr. Denis Corbeil  
Does the cellular environment influence the survival of damaged photoreceptor cells?

Dr. Christian  Bökel  /  Dr. Thomas Weidemann / Prof. Petra Schwille        
Development of reporter constructs for the live imaging of Jak/Stat signalling

Prof. Michael Brand / Dr. Christopher Antos     
Genetic analysis of mechanisms controlling adult neurogenesis and regeneration in adult zebrafish CNS

Prof. Herwig  Gutzeit / Dr. Gilbert Weidinger / Dr. Christopher Antos    
Biology of cultured gonial stem cells in fish

Prof. Michael Kasper / Prof. Ruth Strasser / Dr. Kathrin Barth     
Functional studies of the P2X7 receptor in heart diseases by biochemical investigations employing the Caveolin-1 knockout/knockdown model

Dr. Kai  Loewenbrück  / Prof. Alexander  Storch
Monitoring the effects of environmental factors on physiologic regulation of adult neurogenesis in humans using 1H-MR spectroscopy

Dr. Barbara Ludwig / Dr. Florian Ehehalt / Prof. Stefan Bornstein    
Extended Quality Control of Pancreatic Islets for Clinical Transplantation

Dr. Sophie Pautot / Prof. Günter Lauer / Prof. Bernard Hoflack     
Colloidal alloys as cell carriers for dental implants: A solution to prevent jaw bone resorption after tooth extraction

Dr. Maik  Stiehler / Prof. Martin Bornhäuser      
Optimization of harvest procedure. Three-dimensional cultivation, and osteogenic stimulation of mesenchymal stem cells for bone regeneration

Dr. Claudia Waskow / Prof. Lorenz C. Hofbauer / Prof. Rolf Jessberger    
Prospective isolation of osteoclast precursors

2007

2007 wurden fünfzehn Forschungsprojekte im CRTD Netzwerk gefördert.

 
Dr. Moritz Brandt / Prof. Alexander Storch   
The role of VEGF signaling in adult hippocampal neurogenesis in mice: Induction of cell proliferation and survival in a conditional VEGF-receptor- knockout model

Dr. Monika Ehrhart-Bornstein / Dr. Elly Tanaka
Isolation, Characterization and Long-term Culturing of Adrenal Medullary Chromaffin Progenitor Cells. 

Prof. Katrin Engelmann / Prof. Richard Funk / Dipl-Ing. Monika  Valtink  
Transplantation of immuno-modulated (riboflavin/UVA-treated) corneal transplants in an animal model

Prof. Katrin Engelmann / PD Dr. Dirk Lindemann  
Development of strategies for transient immortalization of primary cells using human corneal endothelial cells (HCEC) as a model system

Dr. Gudrun Goßrau / Dr. Konstantinos Anastassiadis  
ES Cell-derived murine enteric nervous system precursors for cell replacement in SOX10+/- mice, an animal model of Hirschsprung’s disease

Prof. Herwig O. Gutzeit
Spermatogonial Stem cells in Medaka  

Prof. Lorenz C. Hofbauer / Prof. Henning Morawietz
Schützt eine Rank-Ligand-Blockade in einem murinen Modell der Glukokortikoid-Induzierten  Osteoporose
vor  Knochenverlust  und Gefässkalifizierung?
   
Dr. Karsten Kretschmer / Prof. Rolf Jessberger / Prof. Bernard Hoflack  
Protein Expression in Immunosuppression  

Prof. Günter Lauer / Dr. Manolo Hagedorn / Prof. Martin Bornhäuser / Prof. Bernard Hoflack
Approaching mouse non-hematopoietic/ mesenchymal stem cells
   
Prof. Gerhard Rödel / Prof. Martin Bornhäuser   
Biogenesis of the mitchondrial membrane proteome during cellular differentiation   

Prof. Angela Rösen-Wolff / Dr. Michael Gelinsky   
In vitro remodeling of artificial 3D extracellular bone matrix   

Dr. Knut Schäkel  
Programming of regulatory T cells by slanDC (6-sulfoLacNAc expressing dentritic cells)   

Prof. Hans-Joachim Schnittler / Prof. Hans Zwipp / Prof. Francis Stewart / Dr. Federico Calegari  
Functional role of endothelial Eps15 in tissue regeneration   
 
Dr. Attila Tóth / Dr. Konstantinos Anastassiadis / Prof. Rolf Jessberger / Prof. Francis Stewart  
Development of pluripotent spermatogonial stem cell lines for assessment of pluripotency and therapeutic potential.
   
Dr. Gilbert Weidinger / Prof. Carsten Werner 
Functional improvement of zebrafish heart regeneration by delivery of signaling molecules  

2006

2006 förderte das CRTD neun Forschungsprojekte mit "Seed grands" innerhalb des CRTD Netzwerkes:

 
Dr. Andreas Hermann / Prof. Alexander Storch / (Prof. Carsten Werner)
Bridging transplantation for reconstructing the nigrostriatal dopaminergic pathway: Combining orthotopic transplantation of stem cell-derived dopaminergic neurons and collagen matrix-orientated axonal outgrowth

Prof. Klaus-Peter Günther / Prof. Martin Bornhäuser
Evaluation of stem-cell-loaded bone transplants in hip revision surgery. A phase 1/2 clinical trial

Dr. Thomas Illmer / Dr. Markus Schaich
Differential expression of MiRNA duringmyeloid differentiation – lessons learned from malignant hematopoesis
           
Dr. Elly Tanaka / Dr. Matthias Kirsch / Prof. Carsten Werner
Development of a therapeutic strategy for spinal cord injury using stem cells grown in microfabricated polymeric surfaces
       
Dr. Denis Corbeil / Prof. Wieland Huttner
Physiological role of Prominin-2 -Development of a conditional knock-out mouse line        

Prof. Günter Lauer / Dr. Denis Corbeil / Prof. Martin Bornhäuser / Prof. Bernard Hoflack
Establishing optimized techniques for cell tracking in controlled in situ bone regeneration

Dr. Winfried Göttsch / Dr. Sven Seifert / Prof. Henning Morawietz / Prof. Hans-Detlef Saeger
Transcriptionsfaktoren hey2 und COUP-TFII als Determinanten der arteriovenösen Differenzierung von Endothelzellen
       
Dr. Sebastian Brenner / Dr. Martin Ryser
Generation of lentiviral siRNA Libraries for identification of genes involved in hematopoetic stem cell migration and adherence

Prof. Richard Funk / Dr. Denis Corbeil
Oxidative stress in age-related macular degeneration- causative factors, rescue and regeneration