TU Dresden

16.01.2019 Press Release

Behavioural experiments confirm: Increasing the generation of neurons boosts brain function

Image of the extra neurons (in red) artificially generated in the olfactory bulb, the brain area responsible for interpreting odors © CRTD

Scientists from TU Dresden search for new methods to cure neurodegenerative diseases.

Most of the neurons in the human brain are generated from neural stem cells during embryonic development. After birth, a small reservoir of stem cells remains in the brain that keeps on producing new neurons throughout life. But, do these new neurons contribute to brain function? And if so, could we improve brain capacities by increasing their number? The research group of Prof. Federico Calegari at the Center for Regenerative Therapies Dresden (CRTD) of TU Dresden has answered those questions, now published in the renowned EMBO Journal.

"Evolution gave mice an extremely sensitive olfactory system. It is amazing that by adding few neurons we could improve something that seemed already close to perfection", states Prof. Federico Calegari. "This study sets the basis for our research, which now is focused on finding out whether we could apply our strategy as a therapeutic approach in neurodegenerative models."

Complete press release

Publication in EMBO Journal