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02.10.2018

Principles of limb regeneration in salamanders show link to mammals

A regenerated limb in a transgenic axolotl, in which different cell types express different fluorescent proteins. Scale bar is 300 micro metres. © IMP / W. Masselink

Scientists have long argued over which cells enable salamanders to grow back lost limbs. By tracking lineages and characterising individual cells, researchers could now show that connective tissue cells develop stem-cell-like properties and underlie the regeneration of legs. The findings were published in the journal "Science".

Complete press release