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05.04.2016

Breakthrough: Gut bacteria drive growth of stem cells in colon cancer

© CRTD

Colon cancer is one of the most common forms of cancer in Germany. Prof. Dr. med. Sebastian Zeißig, group leader at the DFG Research Center for Regenerative Therapies Dresden (CRTD) - Cluster of Excellence at the TU Dresden and physician at the Department of Medicine I, University Hospital Carl Gustav Carus Dresden, has now shown a decisive role of gut bacteria in the regulation of intestinal stem cells and the development of colon cancer. This discovery promises new therapies not only for cancer but for promoting regeneration of the intestine, for example after chemotherapy.
 

Scientific publication:

"Epithelial calcineurin in the control of microbiota-dependent intestinal tumor development" (NMED-A75820A)

DOI 10.1038/nm.4072