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14.04.2016

Strength through synergies - Dresden scientists generate model systems for retinal disease research

Retinal Organoid under the microscope © CRTD

Scientists at the German Center for Neurodegenerative Diseases (DZNE) and the DFG Research Center for Regenerative Therapies Dresden (CRTD) – Cluster of Excellence at the Technische Universität Dresden have created 3D retina tissue derived from stem cells. To generate these so called retina organoids, the researchers developed a novel protocol that is reliable and more efficient than previous methods. Based on these model systems they are planning to investigate eye diseases and potential strategies for treatment. They report on this in the scientific journal “Stem Cell Reports.”

Scientific publication:

„Retinal Organoids from Pluripotent Stem Cells Efficiently Recapitulate Retinogenesis“, Manuela Völkner, Marlen Zschätzsch, Maria Rostovskaya, Rupert W. Overall, Volker Busskamp, Konstantinos Anastassiadis, Mike O. Karl, Stem Cell Reports,

http://www.sciencedirect.com/science/article/pii/S2213671116000825